Buy Semax + Selank Blend, 10 or 20 mg

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Lab-direct quality — sealed 10-vial packs

Every batch ships straight from the lab that synthesises it — sealed, tamper-evident. Buying direct means you pay the lab-direct rate on every vial, with nothing stacked on top.

Order a sealed 10-vial research pack in the strength your research needs.

Scientific Research Context

What the published literature on the components of Semax + Selank Blend examines. These are findings about each compound in the studies cited, not claims about the blend or the supplied material.

Semax: hippocampal BDNF and TrkB in rats

A single Semax application (50 micrograms per kilogram) raised BDNF protein up to 1.4-fold and TrkB tyrosine phosphorylation 1.6-fold in the rat hippocampus, with 3-fold and 2-fold rises in exon III BDNF and trkB mRNA, and rats showed more conditioned avoidance reactions. [animal, rat]

Semax: serotonin and dopamine systems

In rodents Semax raised striatal tissue 5-HIAA by 25% two hours after dosing and extracellular 5-HIAA up to 180% over one to four hours. On its own it did not change dopamine or its metabolites, but it enhanced the dopamine release and locomotor activity produced by D-amphetamine. [animal, rodent]

Selank: gene expression in rat frontal cortex

Of 84 neurotransmission genes measured, 45 showed significant changes one hour after rats were given Selank or GABA (300 micrograms per kilogram) and 22 at three hours. The one-hour changes of the two correlated, and the authors suggest allosteric modulation of the GABAergic system as one possible mechanism of Selank. [animal, rat]

A shared origin

Both peptides were developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, so the two literatures are largely written by one group and its collaborators. Independent replication in other laboratories is limited in what is cited here.

Overview

In short: A fixed 1:1 research blend of Semax and Selank, offered at 5 mg + 5 mg and 10 mg + 10 mg per vial: two short synthetic neuropeptides from the same research group in one vial.

Key research facts

Two neuropeptide research compounds pre-combined at a fixed 1:1 ratio

Two vial strengths in one product: 5 + 5 mg and 10 + 10 mg

Semax: ACTH(4-10) analogue studied for BDNF/TrkB and monoamine signalling in rodents

Selank: tuftsin-derived heptapeptide studied for gene-expression effects in rat frontal cortex

Both heptapeptides share a C-terminal Pro-Gly-Pro extension

These points summarise lab themes, not human outcomes.

Semax and Selank are close relatives in construction. Each is a seven-residue peptide ending in Pro-Gly-Pro, a tail that is described as protecting the shorter parent sequence from enzymatic breakdown. Semax takes its front end from ACTH(4-10) (Met-Glu-His-Phe), Selank from the tuftsin tetrapeptide (Thr-Lys-Pro-Arg). Both come from the Institute of Molecular Genetics in Moscow, and their published pharmacology is largely rodent work from that group and its collaborators.

The studies cited here are specific. In rats a single Semax application of 50 micrograms per kilogram raised hippocampal BDNF protein 1.4-fold and TrkB phosphorylation 1.6-fold, and a separate study found Semax raised striatal serotonin metabolite 5-HIAA by 25% in tissue and up to 180% extracellularly without changing dopamine on its own. For Selank, a gene-expression study in rat frontal cortex reported significant changes in 45 of 84 neurotransmission genes one hour after rats were given Selank or GABA (300 micrograms per kilogram) and in 22 at three hours, with the gene-expression changes of the two correlating at one hour.

No study of the two as a fixed blend is cited. The ratio does not change between strengths: the 10 mg vial is 5 mg of each peptide and the 20 mg vial is 10 mg of each. Supplied as lyophilised powder for in-vitro and preclinical research only.

Research class: Fixed two-compound research blend

Components: Semax + Selank

Vial strengths: 10 mg, 20 mg per vial, chosen from the pack-size menu

Research focus: Rodent neurotrophin, monoamine and GABA-related gene-expression models

Evidence base: Rat studies of each peptide separately; none on the blend, and no human data cited

Proposed Mechanism

The blend has no combined mechanism. Semax is studied for hippocampal BDNF/TrkB signalling and monoamine effects; Selank for broad changes in neurotransmission-related gene expression with a GABAergic signature. The two are independent compounds sharing a vial.

Pathway Effect Why it matters BDNF and TrkB (Semax) Raised hippocampal BDNF protein and TrkB phosphorylation after a single application in rats The best-quoted Semax mechanism, from rodent tissue Monoamine systems (Semax) Raised striatal 5-HIAA and enhanced amphetamine-induced dopamine release in rodents Neurochemical readouts, not behavioural efficacy Neurotransmission genes (Selank) Significant changes in 45 of 84 genes at one hour in rat frontal cortex after Selank or GABA, with correlated changes A gene-expression signature, not a receptor-binding result No shared pharmacology Each component retains its own published pharmacology Interpret results per component, not for the pair

Deeper dive for scientific readers

The common Pro-Gly-Pro tail and the shared origin make the two look like a matched set, but the cited work does not test them together. All of it is in rodents or rodent tissue, at single doses, and the readouts are neurochemical or transcriptional. A fixed 1:1 vial also removes the ability to vary one peptide against the other; use the stand-alone Semax and Selank products when a design needs that.

Common Questions People Are Asking

What is in the Semax + Selank Blend?

Each vial holds Semax and Selank in a fixed 1:1 ratio: 5 mg of each (10 mg per vial) or 10 mg of each (20 mg per vial). Choose the strength from the pack-size menu.

Why are Semax and Selank sold together?

They are structurally related heptapeptides from the same research institute and are often discussed together. This page cites no study of the pair or of the fixed blend; the evidence listed concerns each peptide separately.

What does the research on each show?

In rats, a single Semax application raised hippocampal BDNF and TrkB, and in rodents it raised a striatal serotonin metabolite. Selank changed the expression of many neurotransmission-related genes in rat frontal cortex. All of it is preclinical and from one research group and its collaborators.

Is there a Certificate of Analysis for this blend?

Not yet. No independent analytical report has been published for this material, so no purity figure is quoted. If one is published it will appear on this page and on our COA page.

Is there human data on this blend?

No study of the blend is cited, and no human study of either peptide is cited on this page. This is laboratory research material, sold strictly for in-vitro and preclinical research and not for human or veterinary use.

Where can I buy Semax + Selank Blend?

Right here - Semax + Selank Blend is supplied directly by New-U Research Compounds on this page, as lyophilised research-grade material, and shipped direct from source worldwide in discreet, tracked packaging.

How much does Semax + Selank Blend cost?

Semax + Selank Blend pricing is shown live on this page, per pack size - 10-vial research packs as standard, with single-vial sample options on selected compounds. Larger vial strengths lower the per-mg cost, and shipping is free on orders over $350.

How do I buy Semax + Selank Blend?

Add the Semax + Selank Blend pack size you need to your cart and check out: enter your shipping details, then choose your payment method - cryptocurrency or card - on the next step.

What payment methods can I use to buy Semax + Selank Blend?

At checkout you can pay by card or crypto. New-U supports BTC and selected stablecoin and network-asset payments across Ethereum, Solana, TRON, Polygon, Base, BNB Chain and Linea. You choose your method after confirming your order.

How fast is shipping, and do you ship worldwide?

Yes - we ship worldwide in discreet, unmarked, tracked packaging; lyophilised peptides are stable through the tracked transit window. Delivery typically takes 6–14 business days, and shipping is free on orders over $350.

Is it legal to buy Semax + Selank Blend?

In the United States, Semax + Selank Blend is sold strictly for laboratory and research purposes only. It is not approved by the FDA for human consumption and is not sold for that purpose. Regulatory status varies by jurisdiction - buyers are responsible for compliance in their own region.

Research use only - all claims made on this site are for testing and research use only.

Pharmacokinetics

Stability Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation. Notes Laboratory research material. No amount, schedule or administration guidance is published or recommended on this page.

Evidence Tier

Overall: Tier 3: Limited / anecdotal

The blend has no evidence base of its own, and this page cites no human study of either peptide. The studies cited are rodent experiments from one research group and its collaborators, with neurochemical and gene-expression readouts. No study of the two as a fixed combination is cited. The material is supplied as unapproved laboratory material.

Tier 2 · Animal

Semax and hippocampal BDNF and TrkB expression in rats

Semax and striatal serotonergic and dopaminergic measures in rodents

Selank and neurotransmission-related gene expression in rat frontal cortex

Databases & peer-reviewed sources

Last reviewed: 14 October 2026 · New-U Research Compounds

Dolotov OV, Karpenko EA, Inozemtseva LS, et al. Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Res 2006. · 2006 · PMID: 16996037 · DOI: 10.1016/j.brainres.2006.07.108

Eremin KO, Kudrin VS, Saransaari P, et al. Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodents. Neurochem Res 2005. · 2005 · PMID: 16362768 · DOI: 10.1007/s11064-005-8826-8

Volkova A, Shadrina M, Kolomin T, et al. Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. Front Pharmacol 2016. · 2016 · PMID: 26924987 · DOI: 10.3389/fphar.2016.00031

PubMed: peer-reviewed literature on Semax + Selank Blend

ClinicalTrials.gov: registered studies on Semax + Selank Blend

Semax + Selank Blend: Wikipedia (search)

WebMD: consumer health reference

BBC News: Health

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Key Characteristics

Fixed 1:1 blend of Semax and Selank in every vial

Two strengths: 5 + 5 mg and 10 + 10 mg per vial

Semax: Met-Glu-His-Phe-Pro-Gly-Pro, an ACTH(4-10) analogue, about 814 Da

Selank: Thr-Lys-Pro-Arg-Pro-Gly-Pro, tuftsin-derived, about 752 Da

Both end in Pro-Gly-Pro and both originate at the same Moscow institute

Cited work is rodent only; no study of the fixed blend is cited

No analytical report published yet; sold as a sealed 10-vial pack, one strength per pack

Specifications

Components Semax + Selank Vial 10 mg Semax 5 mg + Selank 5 mg (10 mg per vial) Vial 20 mg Semax 10 mg + Selank 10 mg (20 mg per vial) Pack 10 vials, one strength per pack Analytical report None published yet Form Lyophilised powder Storage Lyophilised: −20 °C freezer. Reconstituted: 1-6 °C, away from light.

About the Semax + Selank Blend: Research Guide

Semax and Selank are usually described together because they share a structural motif and an origin. Putting them in one vial removes a weighing and reconstitution step for studies that call for both at a matched ratio, and two strengths let the amount per vial follow the design.

The evidence cited is narrow and should be read that way: a handful of rodent studies from one research group, measuring BDNF and TrkB expression, monoamine metabolites and neurotransmission-related gene expression. None examines the pair, and none is a test of behaviour or efficacy in people.

New-U Research Compounds supplies this blend as laboratory research material only. No analytical report for it has been published yet, so no purity figure is quoted. Nothing on this page is medical advice or a recommendation to use it in people or animals.

Dolotov OV, Karpenko EA, Inozemtseva LS, et al. Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Res 2006.

Eremin KO, Kudrin VS, Saransaari P, et al. Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodents. Neurochem Res 2005.

Volkova A, Shadrina M, Kolomin T, et al. Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. Front Pharmacol 2016.

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Descriptive catalog comparison for research sourcing decisions - not dosing guidance.

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Semax + Selank Blend research guide

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Research guide Semax + Selank Blend research guide The blend has no combined mechanism. Read the guide →

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Research peptides. Third-party Certificates of Analysis (Janoshik Analytical & Freedom Diagnostics) are published on the website. Supplied strictly for laboratory research use.

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