Buy Prostamax (KEDP) Peptide Bioregulator

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Order a sealed 10-vial research pack , or add a single-vial laboratory sample alongside your pack to evaluate a compound at smaller scale first. Same source — scaled to whatever your research needs.

Scientific Research Context

What the published literature on Prostamax examines. These are findings about the compound in the studies cited, not claims about the supplied material.

Chromatin melting behaviour

Differential scanning calorimetry of human lymphocyte chromatin showed two melting endotherms shifted to lower temperature by 2.9 and 1.0 °C with Prostamax, with heat redistributed between them. [in vitro, human cells]

Chromatin in cells from donors aged 75-88

Vilon, Epithalon, Livagen, Prostamax and Cortagen were each reported to activate ribosomal genes and decondense chromatin in these cells; Epithalon, Livagen and Prostamax also decondensed chromosome 1 pericentromeric heterochromatin. [in vitro, human cells]

Heterochromatin variants

In cells from donors aged 75-86, Prostamax was reported to lower large pericentromeric heterochromatin variants on chromosomes 1 and 9 and to raise Ag-NOR counts, which the authors interpret as deheterochromatinization. [in vitro, human cells]

Prostate explants

In rat explants of heart, lung, prostate and pancreas from 3-week and 18-month donors, each of four peptides at 0.05 ng/ml stimulated growth of its matching tissue; Prostamax was paired with prostate. [ex vivo, rat tissue]

Overview

In short: Prostamax (Lys-Glu-Asp-Pro, "KEDP") is a four-residue synthetic peptide from the Khavinson bioregulator family, studied in human lymphocyte chromatin assays and rat tissue-explant cultures.

Key research facts

Synthetic Lys-Glu-Asp-Pro (KEDP) tetrapeptide from the Khavinson short-peptide lineage

Studied by differential scanning calorimetry of human lymphocyte chromatin

Examined for cytogenetic endpoints in cells from donors aged 75-88

Tested in rat explants of heart, lung, prostate and pancreas for tissue-matched growth

Distinct from Prostatilen, a bovine prostate extract, and from Cortagen (Ala-Glu-Asp-Pro)

These points summarise lab themes, not human outcomes.

KEDP is Vesugen (Lys-Glu-Asp) with a proline added, and it differs from Cortagen (Ala-Glu-Asp-Pro) only in its first residue. The patent that covers it is titled for regulation of prostate function and describes tests in rodents. The brand name "Prostamax" does not appear in the patent text, so the link between patent and name rests on the identical sequence and on the group's review tables.

The peptide-specific experiments are almost all in human lymphocytes. Differential scanning calorimetry on lymphocyte chromatin shifted two melting endotherms to lower temperature, by 2.9 and 1.0 °C, which the authors read as partial relaxation of the 30-nm fibre. Leukocytes from donors aged 75-88 showed ribosomal gene activation and chromatin decondensation with Prostamax among five tested peptides. The one prostate-tissue experiment is a rat explant study in which Prostamax stimulated prostate explant growth, as three other peptides did for their own tissues.

It is supplied here as a lyophilised research powder for in-vitro and preclinical use. No analytical report for the supplied material has been published yet, so this page quotes no purity figure.

Research class: Synthetic short-peptide bioregulator (Khavinson family)

Sequence: Lys-Glu-Asp-Pro (KEDP)

Research focus: Human lymphocyte chromatin; tissue-matched explant growth in rat prostate

Evidence base: Cell-level and ex-vivo studies from the originating network and a Tbilisi group; no human trial of the peptide

Proposed Mechanism

Prostamax is studied as a short peptide that may relax chromatin in lymphocytes. The mechanism is a hypothesis built from calorimetry and cytogenetics; docking suggests peptide-transporter affinity but no transport was measured.

Pathway Effect Why it matters Chromatin relaxation Chromatin melting endotherms shifted to lower temperature in human lymphocytes The most direct physical measurement; partial relaxation of the 30-nm fibre by the authors' reading Heterochromatin decondensation Pericentromeric heterochromatin on chromosomes 1 and 9 reduced; ribosomal genes activated Cytogenetic endpoints in cells from elderly donors; the sister-chromatid-exchange rate also rose, a conventional stress endpoint Tissue-matched growth Prostate explant growth stimulated, as for other peptides in their own tissues The only tissue-level result tied to the prostate pairing Transporter docking Predicted to dock PEPT1 well (second of 26) and LAT1 and LAT2 poorly A computational ranking; no transport assay

Deeper dive for scientific readers

The Khavinson model proposes that very short peptides enter the nucleus and relax condensed chromatin, switching on genes silenced with age. Prostamax's data fit that picture at the level of calorimetry and cytogenetics, but not at the level of gene expression: none of the cited work measures a prostate-specific transcript. An increase in sister-chromatid exchange accompanied the decondensation in one study, and elevated exchange is conventionally also a marker of cytogenetic stress, so the endpoint cuts both ways. Human data on the synthetic peptide do not exist in the sources found; the human prostate literature concerns Prostatilen, an extract.

Common Questions People Are Asking

What is Prostamax?

Prostamax is the name used for the synthetic tetrapeptide Lys-Glu-Asp-Pro (KEDP), developed in the Khavinson short-peptide programme. The patent behind it is titled for prostate function. It is supplied here as a laboratory research powder only.

Is Prostamax the same as Prostatilen?

No. Prostatilen is a peptide extract from bovine prostate and is studied separately. Prostamax is a defined synthetic tetrapeptide. Human prostate literature that appears in searches concerns the extract, not this peptide.

How does Prostamax differ from Cortagen?

They share Glu-Asp-Pro at the end. Prostamax starts with lysine (Lys-Glu-Asp-Pro) and Cortagen with alanine (Ala-Glu-Asp-Pro). They have different formulas and masses and are listed as separate compounds.

Is there a Certificate of Analysis for Prostamax?

Not yet. No independent analytical report has been published for this material, so no purity figure is quoted.

Is there human data on Prostamax?

The human-cell work is in vitro on lymphocytes. No human study of the synthetic peptide and no registered trial were found. Prostamax is sold strictly for in-vitro and preclinical research, not for human or veterinary use.

Where can I buy Prostamax?

Right here - Prostamax is supplied directly by New-U Research Compounds on this page, as lyophilised research-grade material, and shipped direct from source worldwide in discreet, tracked packaging.

How much does Prostamax cost?

Prostamax pricing is shown live on this page, per pack size - 10-vial research packs as standard, with single-vial sample options on selected compounds. Shipping is free on orders over $350.

How do I buy Prostamax?

Add the Prostamax pack size you need to your cart and check out: enter your shipping details, then choose your payment method - cryptocurrency or card - on the next step.

What payment methods can I use to buy Prostamax?

At checkout you can pay by card or crypto. New-U supports BTC and selected stablecoin and network-asset payments across Ethereum, Solana, TRON, Polygon, Base, BNB Chain and Linea. You choose your method after confirming your order.

How fast is shipping, and do you ship worldwide?

Yes - we ship worldwide in discreet, unmarked, tracked packaging; lyophilised peptides are stable through the tracked transit window. Delivery typically takes 6–14 business days, and shipping is free on orders over $350.

Is it legal to buy Prostamax?

In the United States, Prostamax is sold strictly for laboratory and research purposes only. It is not approved by the FDA for human consumption and is not sold for that purpose. Regulatory status varies by jurisdiction - buyers are responsible for compliance in their own region.

Research use only - all claims made on this site are for testing and research use only.

Pharmacokinetics

Stability Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Notes Laboratory research material. No human dosing exists for this compound and none is published or recommended here.

Evidence Tier

Overall: Tier 3: Limited / anecdotal

Prostamax has a small preclinical record of human lymphocyte chromatin assays, calorimetry, cytogenetics and one rat explant study, all at cell or tissue level and all from the originating network or a Tbilisi collaborator. There is no human study of the synthetic peptide and no independent replication. It is supplied as unapproved laboratory material.

Tier 2 · Animal

Growth of prostate explants from young and 18-month-old rats in organotypic culture

Databases & peer-reviewed sources

Last reviewed: 13 October 2026 · New-U Research Compounds

Khavinson VKh, Lezhava TA, Malinin VV. Effects of short peptides on lymphocyte chromatin in senile subjects. Bull Exp Biol Med 2004. · 2004 · PMID: 15085253 · DOI: 10.1023/b:bebm.0000024393.40560.05

Meskhi T, Khachidze D, Barbakadze Sh, et al. The influence of the peptide bioregulator prostamax on heterochromatin of human lymphocytes in situ. Biofizika 2004. · 2004 · PMID: 15612551

Dzhokhadze TA, Buadze TZh, Gaiozishvili MN, et al. Deheterochromatinization of the chromatin in old age induced by oligopeptide bioregulator (Lys-Glu-Asp-Pro). Georgian Med News 2012. · 2012 · PMID: 23221144

Zakutskii AN, Chalisova NI, Ryzhak GA, et al. The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats. Adv Gerontol 2006. · 2006 · PMID: 17152728

Solovyev AY, Tarnovskaya SI, Chernova IA, et al. The interaction of amino acids, peptides, and proteins with DNA. Int J Biol Macromol 2015. · 2015 · PMID: 25841380 · DOI: 10.1016/j.ijbiomac.2015.03.054

Khavinson V, Linkova N, Kozhevnikova E, et al. Transport of Biologically Active Ultrashort Peptides Using POT and LAT Carriers. Int J Mol Sci 2022. · 2022 · PMID: 35887081 · DOI: 10.3390/ijms23147733

Khavinson VK, Linkova NS, Rudskoy AI, et al. Feasibility of Transport of 26 Biologically Active Ultrashort Peptides via LAT and PEPT Family Transporters. Biomolecules 2023. · 2023 · PMID: 36979488 · DOI: 10.3390/biom13030552

PubMed: peer-reviewed literature on Prostamax

ClinicalTrials.gov: registered studies on Prostamax

Prostamax: Wikipedia (search)

WebMD: consumer health reference

BBC News: Health

CNN Health: “Peptides: what to know about the wellness trend”

Sky News: “Can peptides make America healthy again?”

Sky News: “Inside the exploding US peptides craze” (video)

Sky News Australia: “Black market peptide trade explodes as influencers fuel uptick in use”

Sky News Australia: “Backyard peptide boom sparks alarm” (video)

Sky News Australia: “Oprah reveals struggle with shame of weight-loss drugs”

Key Characteristics

Four-residue peptide: Lys-Glu-Asp-Pro (KEDP)

Vesugen (Lys-Glu-Asp) plus a C-terminal proline

Differs from Cortagen (Ala-Glu-Asp-Pro) at residue 1 only

Lymphocyte chromatin calorimetry and cytogenetics, plus rat explants

Not Prostatilen, which is a prostate extract

Supplied as 10 × 20 mg lyophilised vials; no analytical report published yet

Specifications

Sequence Lys-Glu-Asp-Pro (KEDP) Residues 4 Molecular Formula C 20 H 33 N 5 O 9 Molecular Weight 487.51 Da (average, free peptide) Form Lyophilised powder Pack 10 vials × 20 mg Family Khavinson short-peptide bioregulator Analytical report None published yet Storage Lyophilised: −20 °C freezer. Reconstituted: 1-6 °C, away from light.

About Prostamax (KEDP): Short-Peptide Bioregulator Research Guide

The European patent behind Prostamax (EP 1 353 939 B1) has a priority date of January 2001 and was published in 2004 under a title that refers to a tetrapeptide regulating prostate functions. The first peer-reviewed papers that name Prostamax date to 2004. The lymphocyte papers cited for Prostamax are about lymphocytes, not prostate tissue.

Prostamax is Lys-Glu-Asp-Pro, a different molecule from Livagen (Lys-Glu-Asp-Ala) or Cortagen (Ala-Glu-Asp-Pro). The formula C20H33N5O9 and average mass 487.51 Da on this page are computed from Lys-Glu-Asp-Pro and match the compound record.

New-U Research Compounds supplies Prostamax as a lyophilised research powder in sealed 10-vial packs of 20 mg vials. No analytical report for the supplied material has been published yet, and this page makes no purity or certificate claim. It is for in-vitro and preclinical research only and nothing here is medical advice.

Khavinson VKh, Lezhava TA, Malinin VV. Effects of short peptides on lymphocyte chromatin in senile subjects. Bull Exp Biol Med 2004.

Meskhi T, Khachidze D, Barbakadze Sh, et al. The influence of the peptide bioregulator prostamax on heterochromatin of human lymphocytes in situ. Biofizika 2004.

Dzhokhadze TA, Buadze TZh, Gaiozishvili MN, et al. Deheterochromatinization of the chromatin in old age induced by oligopeptide bioregulator (Lys-Glu-Asp-Pro). Georgian Med News 2012.

Zakutskii AN, Chalisova NI, Ryzhak GA, et al. The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats. Adv Gerontol 2006.

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Research peptides. Third-party Certificates of Analysis (Janoshik Analytical & Freedom Diagnostics) are published on the website. Supplied strictly for laboratory research use.

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