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    Vesugen peptide: Metabolic / Longevity research guide

    In short: Vesugen (Lys-Glu-Asp / KED, lab code T-38) is a synthetic tripeptide from the Khavinson short-peptide family, studied in vascular endothelial cultures, neuronal models and stem-cell cultures. It is studied in preclinical (cell and animal) research and is supplied strictly for laboratory use, not for human or clinical use.

    Not medical advice. Vesugen is a research compound. This guide does not provide dosing, diagnosis, therapy recommendations, or claims about effects in humans.

    Vesugen at a glance

    Compound type
    Research peptide
    Research category
    Metabolic / Longevity
    Also known as
    Vesugen, Vezugen, KED, T-38, Lys-Glu-Asp, H-Lys-Glu-Asp-OH, lysyl-glutamyl-aspartic acid, Khavinson vascular bioregulator
    Molecular weight
    390.39 Da
    Evidence context
    Preclinical / research use only
    Regulatory status
    Not an approved medicine. Supplied as a research compound
    Last reviewed
    13 October 2026

    What to know first

    Compound Vesugen Research class Metabolic / Longevity Available pack sizes 10 × 20 mg Storage Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight.

    Details and limits sit in the sections below. Research use only. No unsupported scientific claims are added here.

    What Vesugen is

    Vesugen (Lys-Glu-Asp, "KED") is a three-residue synthetic peptide from the Khavinson bioregulator family, studied in vascular endothelial, neuronal and stem-cell cultures.

    One-paragraph overview from our research datasheet. Still scientific, but faster to read than the full mechanism list below.

    Vesugen (Lys-Glu-Asp / KED, lab code T-38) is a synthetic tripeptide from the Khavinson short-peptide family, studied in vascular endothelial cultures, neuronal models and stem-cell cultures.

    Research contexts

    Peer-reviewed papers discuss Vesugen in specific lab settings. The points below reflect research questions, not health claims.

    Research vs. personal use: Literature describes experiments in cells and animals. That is distinct from real-world use. Our products are for laboratory research only.

    Typical study contexts

  • Mitochondrial stress, NAD+/redox biology and nutrient-sensing pathways.
  • Enzyme activity, gene expression or endurance-style animal readouts.
  • Synthetic Lys-Glu-Asp (KED) tripeptide from the Khavinson short-peptide lineage, lab code T-38.
  • Studied in vascular endothelial cultures for endothelin-1, connexin, sirtuin-1 and Ki-67.
  • Examined in a transgenic mouse model of neuronal spine loss, with Pinealon as comparator.
  • Tested in pineal organotypic cultures and human mesenchymal stem-cell cultures.
  • Why Metabolic / Longevity research matters

    Researchers study these compounds for mitochondrial function and cellular energy stress. Ageing and metabolic disease models are common.

    Mechanisms (technical review)

    Our datasheet lists mechanistic themes from preclinical work. These are research endpoints, not health claims.

  • Synthetic Lys-Glu-Asp (KED) tripeptide from the Khavinson short-peptide lineage, lab code T-38
  • Studied in vascular endothelial cultures for endothelin-1, connexin, sirtuin-1 and Ki-67
  • Examined in a transgenic mouse model of neuronal spine loss, with Pinealon as comparator
  • Tested in pineal organotypic cultures and human mesenchymal stem-cell cultures
  • The shared stem of Livagen, Pancragen, Testagen and Prostamax
  • Lab handling & preparation

  • Storage: Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight.. See the storage guide.
  • Published pharmacokinetic context: Laboratory research material. No human dosing exists for this compound and none is published or recommended here.
  • Purity check: Use the COA reading guide and the published Certificates of Analysis (no current certificate is listed for Vesugen yet).
  • Common Questions People Are Asking

    What is Vesugen?

    Vesugen is the name used for the synthetic tripeptide Lys-Glu-Asp (KED), lab code T-38, in the Khavinson short-peptide literature, which pairs it with vascular tissue. It is supplied here as a laboratory research powder only.

    How is Vesugen related to Livagen, Pancragen, Testagen and Prostamax?

    Each of those is Lys-Glu-Asp with one more residue at the end: alanine for Livagen, tryptophan for Pancragen, glycine for Testagen and proline for Prostamax. That is a sequence observation; the papers do not state a derivation.

    What does the research on Vesugen show?

    In endothelial cultures it was reported to normalise endothelin-1 and raise connexin, sirtuin-1 and Ki-67. In a transgenic mouse model it was reported to prevent dendritic spine loss, and further cell studies cover pineal, stem-cell and induced-neuron cultures. All of it is preclinical and from one research network.

    Is there a Certificate of Analysis for Vesugen?

    Not yet. No independent analytical report has been published for this material, so no purity figure is quoted.

    Is there human data on Vesugen?

    Two small Russian-language reports exist; both are single-group and neither is relied on here. No randomised trial was found. Vesugen is sold strictly for in-vitro and preclinical research, not for human or veterinary use.

    Is this page medical advice? Can I use Vesugen for my health?

    No, and no. This article is educational only. We do not provide dosing, medical recommendations, or health claims. Our products are sold strictly for laboratory research, not for personal use of any kind.

    Where do I find Vesugen specs, purity certificates and pricing?

    Open the shop listing via “View product details.” There you will see concentration, purity grade, and available SKUs with current pricing. No current Certificate of Analysis is published for Vesugen yet; published certificates are listed at /coa.

    Related peptide guides

    Other compounds researchers often read about alongside Vesugen.

  • Cartalax: Metabolic / Longevity research guide
  • Pinealon: Metabolic / Longevity research guide
  • Epitalon: Metabolic / Longevity research guide
  • Livagen: Metabolic / Longevity research guide
  • Continue Vesugen research

    Analytical evidence, comparisons and current research for this compound. Research use only.

  • Research area Cognitive & longevity research The neuropeptide and longevity research area - nootropic and geroprotective peptides and related compounds studied in cognition… Explore the research area →
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  • Scientific sources & further reading

    Primary literature and registries for Vesugen, plus mainstream coverage of the peptide category. Research use only - not medical advice.

    Databases & literature:

  • PubMed: peer-reviewed literature on Vesugen
  • ClinicalTrials.gov: registered studies on Vesugen
  • Vesugen: Wikipedia (search)
  • Peptides in the news:

  • WebMD: consumer health reference
  • BBC News: Health
  • CNN Health: “Peptides: what to know about the wellness trend”
  • Sky News: “Can peptides make America healthy again?”
  • Sky News: “Inside the exploding US peptides craze” (video)
  • Sky News Australia: “Black market peptide trade explodes as influencers fuel uptick in use”
  • Sky News Australia: “Backyard peptide boom sparks alarm” (video)
  • Sky News Australia: “Oprah reveals struggle with shame of weight-loss drugs”
  • Ready to order? View full product specs

    Access concentration, batch info, variants, and current pricing on our shop.

    Also known as: Vesugen, Vezugen, KED, T-38, Lys-Glu-Asp, H-Lys-Glu-Asp-OH, lysyl-glutamyl-aspartic acid, Khavinson vascular bioregulator

    PRECISION. PURITY. PERFORMANCE.

    Research peptides. Third-party Certificates of Analysis (Janoshik Analytical & Freedom Diagnostics) are published on the website. Supplied strictly for laboratory research use.

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